Thiel Award goes to Philipp Hartmann

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Great honor: Philipp Hartmann (right) receives the Thiel Award, handed over by Prof. Frank Neese, Managing Director at the Max-Planck-Institut für Kohlenforschung. | Quelle: Sarah Gombert | Copyright: MPI Kofo | Download

Chemically modifying proteins plays a key role in investigating biological processes and gaining a better understanding of the structure of the proteins themselves. However, the task is not trivial. In his work "Chemoselective umpolung of thiols to episulfoniums for cysteine bioconjugation", published in the journal Nature Chemistry, PhD student Philipp Hartmann from the Department of Organic Synthesis has shown how an amino acid can be elegantly turned into a versatile reaction partner. For this achievement, the young Hesse native has now been honored with the Thiel Award of the Max Planck Institute für Kohlenforschung.

"The Max Planck Institute presents the Thiel Award once a year," explains Prof. Frank Neese, Managing Director of the Institute. With this award, named after the Institute Director Walter Thiel, who died suddenly in 2019, the Kohlenforschung always honors a special young talent in the field of chemistry. "That would have been entirely in line with Walter Thiel's wishes," emphasizes Neese, "because Walter was always very committed to promoting young chemists."

In his keynote speech, Philipp Hartmann describes, among other things, how thianthrenium chemistry, as developed in the Department of Organic Synthesis under the direction of Prof. Dr. Tobias Ritter, can help to specifically modify building blocks of proteins such as the amino acid cysteine. According to the young chemist, this method could contribute to the investigation and quantification of complex biological systems in the future.

The presentation of the Thiel Award is traditionally an important part of an institute seminar - an event that primarily aims to encourage the many young researchers at Kahlenberg to look beyond their own horizons and engage with the projects of their colleagues.

And so many Kohlenforschung scientists listened to the second lecture of the day, which this time was given by the new group leader at the institute, Guanqi Qiu. The young scientist, who has been setting up her independent research group at the Kohlenforschung since November, is particularly interested in the intrinsic properties of reactions - in other words, those aspects that happen independently of thermodynamics.

"Take the opportunity, be inspired - and perhaps there will be one or two opportunities for new collaborations," said Neese to the many international scientists who attended the seminar.

Wissenschaftlicher Ansprechpartner:
Prof. Dr. Frank Neese
Department of Molecular Theory and Spectroscopy
Max-Planck Institut für Kohlenforschung
Kaiser-Wilhelm-Platz 1
D-45470 Mülheim an der Ruhr
Germany
E-Mail: Frank.Neese@kofo.mpg.de

Originalpublikation:
https://www.nature.com/articles/s41557-023-01388-7