New study at the FBN decodes the genome of the African catfish
Scientists at the Research Institute for Farm Animal Biology (FBN) in Dummerstorf have decoded the genome of the African catfish (Clarias gariepinus) in collaboration with international partners.
The study (Nguinkal JA et al., Sci Data 11, 2024), which was recently published in the journal Scientific Data, represents a milestone for genetic research on the animal and aquaculture husbandry.
The genome of the African catfish decoded
The African catfish is one of the most important species in global fish production. It is widely used in aquaculture due to its rapid growth rate, adaptability to different environmental conditions and resistance to disease. Despite its importance, the genome of this species has so far only been partially decoded. With the help of the latest sequencing technologies, it has now been possible to decode the genome in detail and analyse it completely.
In the current study, a haplotype-resolved, near complete (T2T, ‘telomere-to-telomere’) genome assembly was performed, which represents 99.96% of the genome. This makes it possible to analyse the inherited parental chromosomes independently of each other, which is particularly important for understanding genetic diversity. The genome of the African catfish comprises approximately 969.62 million base pairs and its diploid chromosome set consists of 56 chromosomes.
Tool for further research
“The genome decoding not only enables us to further improve the breeding and keeping of the African catfish in aquaculture, but also provides valuable insights into the evolutionary biology of fish,” says Prof Dr Tom Goldammer, head of the Fish Genetics working group at the FBN. “With our research, we have taken a major step towards further research into this fascinating species. The data is a valuable tool for future studies and will be made available to the scientific community worldwide,” Goldammer continued.
Genome project strengthens catfish breeding in Mecklenburg-Western Pomerania
The African catfish is particularly adaptable and, in addition to gill breathing, has also developed the ability to utilise oxygen from the air. The 50 genes that control this mechanism have now been identified, which can further advance evolutionary research and enable exciting research approaches to this physiological peculiarity. Following the reference genome for the pike perch (Nguinkal et al., Genes (Basel) 10, 2019), the FBN has now created the basic prerequisite for modern breeding approaches for this species with the African catfish, another economically relevant aquaculture fish species.
In Germany, for example, Nutrition & Food GmbH in Mecklenburg-Western Pomerania produces around 500 tonnes of this fish species every year for commercial kitchens, hospitals, schools and restaurants. The knowledge gained will help to improve animal welfare in African catfish farming and reduce emissions in production in the
future.
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Picture 1:
The Fish Genetics working group at the FBN has completely sequenced the reference genome for the African catfish ©Goldammer/FBN
Picture 2:
African catfish in aquaculture farm ©Wenzel/Nutrition & Food GmbH
About the FBN:
The Research Institute for Farm Animal Biology (FBN), based in Dummerstorf near Rostock in the federal state of Mecklenburg-Western Pomerania (formerly the Research Institute for the Biology of Farm Animals), was founded in 1993 and is dedicated to application-oriented basic research in the field of farm animal biology. Around 300 employees carry out interdisciplinary research and work in the four focus areas: Individualising farm animal husbandry, farming animals in sustainable resource cycles, coping with critical life phases of farm animals and promoting diversity in animal farming. The aim is to research responsible animal farming as an indispensable component of sustainable agriculture. The animal is the focus of scientific research, from the genome to metabolism and behaviour.
Research Institute of Farm Animal Biology (FBN)
Wilhelm-Stahl-Allee 2, 18196 Dummerstorf
Director Prof Dr Klaus Wimmers
T +49 38208-68 600
E wimmers@fbn-dummerstorf.de
Press and public relations
Jan Ostermayer
T +49 38208-68 605
E presse@fbn-dummerstorf.de
www.fbn-dummerstorf.de
LinkedIn: @forschungsinstitut-nutztierbiologie-fbn
X: @FBNDummerstorf
Instagram: @forschungsinstitut_fbn
Wissenschaftlicher Ansprechpartner:
Prof. Dr. Tom Goldammer
Research Institute for Farm Animal Biology (FBN)
Haed of working group Fish Genetics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
tel.: +49 38208 68-708
email: tomgoldammer@fbn-dummerstorf.de
Originalpublikation:
https://www.nature.com/articles/s41597-024-03906-9
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